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PENTAGUM

The first barrier in a layered defense strategy

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When readiness is paramount

Designed to support field dental care by functioning as a barrier to oral biofilms in austere environments when the warfighter has limited access to routine hygiene.
 

Neutralizing the enemy

MIIP-E2, the key active ingredient in our gum, is a potent and safe multifunctional innate immune glycoprotein found in mammals produced by a patent-pending process to retain all native activity. 
*Not synthetically engineered or modified

 
Functions as an early-life broad-spectrum, yet highly specific deterrent of infection.
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Increases surface layer integrity in the buccal mucosa as an inhibitor and disruptor of bacterial biofilms.

FDA Medical Device application pending.

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Broad-spectrum capabilities

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Our commitment to the warfighter

With support and guidance from the United States Army Medical Research and Development Command, we formulated our unique naturally occurring antimicrobial molecule into a safe, oral elastomer format to advance existing MRE components by adding a preventative oral care layer

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Next-gen oral care

Bioactive functionality and Awareness: 
All-in-one

Design

Few oral care products look any different than the next.
Gum is gum, but this one is not like any of the rest.
We took inspiration from our collaborators in the U.S. Army and emulated the design of the most iconic shape known at the Department of Defense, the Pentagon, to make sure you knew which one possessed the added protection you need.

Why gum?

Our initial format was as an orally dissolvable tablet. When we sat down at the USAMRDC to introduce the active ingredient we developed at the beginning of the Covid pandemic, their first question was, 'can you put it in something we already give the warfighter?'
In every MRE is a piece of xylitol gum. Why reinvent the wheel when you can just make it better. We infused our molecule into an even higher quality pharmaceutical-grade sugar-free gum base.

Functionality

Our initial concept was based on developing the first pharma-grade ultra pure version of a well-known innate immune protein found in agriculture. In the oral cavity, it could eventually serve to limit long-term bacterial biofilm adhesion, reduce cavities and even limit the transmission of other pathogens.

Advanced Formulation

Pentagum uses an ultra-high quality pharma-grade gum base that is compressed without the use of heat to limit disruption of the active molecule. We add anhydrous caffeine to the AC version to limit the rapid on/off effects and unpleasant side effects of less expensive stimulants to assure attention to detail.

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